Automatic continuous on-line monitoring of salicylic acid and acetylsalicylic acid in pharmaceuticals

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Automatic continuous on-line monitoring of salicylic acid and acetylsalicylic acid in pharmaceuticals

An asymmetrical FIA merging-zones manifold based on the dual injection of two sample microvolumes was developed for the simultaneous determination of salicylic acid and acetylsalicylic acid in pharmaceutical preparations at a sampling frequency of 30/h. The complex formed between the Fe(III) reagent continuously introduced in the system and salicylic acid was monitored photometrically at 520 nm...

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The protein binding of acetylsalicylic acid and salicylic acid.

Quantitative experiments to study the binding of acetylsalicylic acid (ASA) and salicylic acid (SA) by human serum albumin (HSA) were carried out using ‘4C-labeled ASA or SA and gel filtration to separate the free from the bound forms. Two binding procedures were employed: the ASA or SA was incubated with the HSA, or the mixture was placed in an equilibrium dialysis cell. By withdrawing samples...

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Pharmacokinetics and in vitro efficacy of salicylic acid after oral administration of acetylsalicylic acid in horses

BACKGROUND Although acetylsalicylic acid (ASA) is not frequently used as a therapeutic agent in horses, its metabolite SA is of special interest in equestrianism since it is a natural component of many plants used as horse feed. This led to the establishment of thresholds by horse sport organizations for SA in urine and plasma. The aim of this study was to investigate plasma and urine concentra...

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Effect of Gibberllic acid and Salicylic acid on Secondary metabolites in leaf of Curcuma longa L.

Background & Aim: Turmeric, scientifically named (Curcuma longa L.), a member of ginger (Zingiberaceae) family, is a perennial plant, with pharmaceutical properties and with a rhizome. This plant has many medicinal characteristics including anti-cancer, anti-bacteria and anti-hepatitis properties. Experimental: To study the effects of Gibberellic acid and Salicylic acid on leaf, the r...

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ژورنال

عنوان ژورنال: Journal of Automatic Chemistry

سال: 1990

ISSN: 0142-0453

DOI: 10.1155/s1463924690000335